microscopic transsphenoidal surgery for pituitary adenomas in children and adolescents
نویسندگان
چکیده
background & aim: we described the presentation, management and subsequent treatment outcomes of children and adolescents diagnosed with a pituitary adenoma in a joint neuroendocrine setting followed up by a single service as well as assessing long-term outcomes in terms of endocrine status and neurology symptoms. methods & materials/patients: a total of 21 participants with histologically verified pituitary adenoma between january 2011 and june 2014 were studied. patients' data from clinical, radiological and pathological records were analyzed using spss (version 16). results: all these children and adolescents with pituitary adenomas were managed with microscopic transsphenoidal surgery. the most common symptom was cushing (47.6%, n=10). the functional type (76.2%, n=16) was more than the non-functional. the post-operative control mri of most of them was clear (90.5%, n=19). the lab control of most of them was normal (76.2%, n=16). apoplexy was seen in 5 patients (33.8%). gross-total resection (gtr; 100% tumor removal as judged by early post-operative imaging) was achieved in 19 cases. only one of these patients showed evidence of radiologic recurrence. conclusion: in our study, all patients underwent microscopic transsphenoidal surgery due to limitation of endoscopic approach in pediatric and avoided wide anatomical deficit. doing a comparative study between these two approaches will bring about promising results.
منابع مشابه
Microscopic Transsphenoidal Surgery for Pituitary Adenomas in Children and Adolescents
Background & Aim: We described the presentation, management and subsequent treatment outcomes of children and adolescents diagnosed with a pituitary adenoma in a joint neuroendocrine setting followed up by a single service as well as assessing long-term outcomes in terms of endocrine status and neurology symptoms. Methods & Materials/Patients: A total of 21 participants with histologically v...
متن کاملMicroscopic Transsphenoidal Surgery for Pituitary Adenomas in Children and Adolescents
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Introduction: The endoscopic transsphenoidal approach for pituitary adenomas and other sellar lesions is quickly becoming the procedure of choice in their surgical management. The most common approach is binostril three-hand technique which requires a large exposure and subjects both nasal cavities to potential trauma. To reduce nasal morbidity, we employ a mononostril two-hand technique with t...
متن کاملAdenomas Pituitary in Children And Adolescents
Pituitary tumors are rare in childhood and adolescence, with a reported prevalence of up to 1 per million children. Although pituitary tumors are rare in childhood and adolescence, and are typically histologically benign, significant morbidity may result due to their location, mass effect, and/or interference with normal pituitary hormone functions. The frequency of macro adenomas and aggressiv...
متن کاملOlfactory functions after transsphenoidal pituitary surgery: endoscopic versus microscopic approach.
OBJECTIVES/HYPOTHESIS Olfactory disturbances could be observed following transsphenoidal pituitary surgeries. To our knowledge, no previous comparative studies on olfactory functions after transsphenoidal endoscopic and microscopic approaches have been performed. STUDY DESIGN Prospective study comparing olfactory functions between endoscopic and microscopic transsphenoidal pituitary surgery. ...
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عنوان ژورنال:
iranian journal of neuro surgeryجلد ۱، شماره ۳، صفحات ۰-۰
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